Injectables 注射项目

What are injectables?
As the name suggests, injectables are synthetic materials that are introduced to different areas of the face and the body with a needle or a cannula (blunt tip needle). The traditional injectables include three major categories: 1) Neuromodulators and 2) Dermal Fillers 3) Fat Emulsifying Agent.

何为注射类项目?

注射类项目是对于将药品或者填充品通过针剂方式注射到真皮层以下项目的统称。 传统意义上的注射类包含一下啊三大类:1)肉毒素类; 2)软组织填充类; 3)溶脂类。

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Neuromodulators:

These agents contain proteins derived from Botulinum Toxin A. Botulinum Toxin A is found in nature (yes, in spoiled canned food or bad honey).  It blocks the transmission of signals to muscles and in turn relaxes them. This unique action was harnessed by medical professionals to treat muscle spasms and increased muscle tones. It has also been widely adopted by aesthetic providers around the world to treat dynamic wrinkles since the 1990s. This treatment is safe and effective, tried and true. The result can last anywhere between 4-6 months depending on the individual. It is one of the most loved treatments in aesthetic medicine because of its reliability and low risk profile.   

肉毒素类

肉毒素来自于于自然的一种阻断神经传导的蛋白。通过阻断神经传导的方式,肉毒素可以放松肌肉从而达到治疗肌肉痉挛硬化等病症。自1990年代起,肉毒素被广泛的使用在医美范畴,用来放松面/颈部肌肉从而达到治疗和预防皱纹的效果,普遍来说肉毒的功效可达到4-6个月。这个医美项目自大众慢慢开始接受它起,便越来越风行。总结来看还是因为它可靠的效果,安全性高和副作用小这几个方面。 


There are now five available neuromodulators on the market. They act similarly to one another with only a few small differences:
美国市面上现在有5个不同的肉毒素产品。 功效方面并没有特别的差异,但是每个种类还是有自己的一点长处:

Botox®:
This is the FIRST neuromodulator on the market. Providers are most familiar with this particular product. It remains the gold standard product that providers compare to. 

保妥适肉毒
市面上最早出产的肉毒素产品,因此这是注射者最为熟悉的一个产品。至今为止新的肉毒素都要和保妥适来比对效果,可谓是肉毒素产品里的金标准。

Dysport®:
The second longest standing product in this category. The medicine when injected can spread slightly further than the rest of the neuromodulators. It is ideal for treating larger muscle groups or stronger muscles.

丽舒妥肉毒
市面上对战保妥适最长时间的一个产品也是有着第二长历史的肉毒素。此款肉毒素乃是所有肉毒素中分子量最大,因此散播程度最广的一个产品。 由于这个特殊的性质,它非常适合用于强肌肉群或者大肌肉群(例如咬肌,小腿腓肠肌,肩部斜方肌等)。

Xeomin®: 
The PUREST neuromodulators on the market. It is less likely to produce tolerance (needing more and more injection to maintain the same level of results). 

天使肉毒
天使肉毒乃是对于肉毒素蛋白做出最少改变的一款产品。因此也经常被大家称为“最纯肉毒”,最不容易产生抗药性的一款肉毒素。因为此款肉毒素最为接近肉毒蛋白的原始结构,相对药性弱一点点,需要的量也略微大一点

Jeuveau®: 
Comparable to other products (i.e. Botox) but generally have a lower price point than others because of the newness of the product. 

新肉毒
名字可见属于最新几款肉毒之一,原产于韩国。药效与原保妥适类似但普遍来说价格偏低。是入门级的好选择。由于此产品比较新,普遍注射者对它的经验都相对少一些。 

Daxxify®: 
NEWEST on the market. Not widely available but claims to have longer duration (6 months median duration compared to 4 months duration of all other products)

Daxxify(没有中文名)
最新的肉毒,还没有完全开放性的面市。但是根据文献看,此产品将会有较长的药效可长达6个月或以上。

Dermal Fillers:

Dermal Filler is a blanket term that describes biocompatible materials that can be injected into subdermal, dermal, subcutaneous, and perichondrial tissues for restoring volume. There are two major categories of dermal fillers: 1) hyaluronic acid fillers; 2) biostimulatory fillers. 

软组织填充类

软组织填充类包含了所有可注射于真皮层皮下组织筋膜骨膜层,与生物体相匹配的材料。这些材料又可以分成两大类:1)交联玻尿酸; 2)可再生材料。

Hyaluronic Acid Filler
Hyaluronic acid is a naturally occuring ground substance within the matrix of human skin. It helps the skin to hold on to water. Therefore, having an abundance of hyaluronic acid will produce healthier skin texture, improve skin moisturization and present you with an overall plumpness. This is also why hyaluronic acid is in many skin care products. However, when we talk about Hyaluronic Acid Filler, we are talking about “crosslinked” hyaluronic acid. In these fillers, multiple hyaluronic acid molecules (i.e, hundreds) are held together by a back bone agent. When the cross linked hyaluronic acid filler is injected into the skin, instead of permeating into the skin basement membrane, it will be held in place by the backbone. 

The benefit of this type of filler is that 1) depending on the specific crosslinking mechanism, the filler can be soft or stiff for different applications; 2) it is reversible (** to a certain degree).  For those two specific reasons, hyaluronic acid fillers have become the most popular soft tissue filler in the past decade all around the world. 

Filler choices we offer: Juvederm®, Restylane®, Teoxane RHA®

交联玻尿酸填充剂
玻尿酸,也为透明质酸,本来就是属于人体皮肤细胞基地组织的一部分,它能帮助皮肤细胞和组织更好的抓住水份。 因此,拥有饱满玻尿酸的皮肤会显得更加健康,水润和充盈。这也是为什么众多的护肤产品中都含有玻尿酸。填充物中的玻尿酸是“交联”的玻尿酸。 交联玻尿酸由两部分组成,一小部分交联剂和成百上千的透明质酸单体。 因为交联的玻尿酸不完全为液体,当它被注射入体内时,它可以吸收水分的同时保留注射后的形态。 

交联玻尿酸有明显的优点。首先,根据不同的交联手法和玻尿酸分子量,市面上有众多硬度不同的产品可适用于不同的注射位置和注射功效。其次,交联玻尿酸可溶,因此相对来说有可恢复性。这两个特殊的性质,交联玻尿酸是现在市面上最受欢迎的注射剂。

可选择的玻尿酸: 乔雅登 瑞蓝 泰奥(熊猫针)

Biostimulatory Filler
This category of fillers, when injected, can stimulate the body to produce collagen and elastin. Collagen and elastin are essential for maintaining volume and firmness of the skin. These types of filler will only have a small amount of volume but overtime your body will produce collagen to lift and tighten the treated areas. 

可再生型填充剂
这个类型的填充剂都为高聚合生物制剂,当注射到身体后会激发炎症反应刺激自体产生胶原蛋白和弹性蛋白的产生。 胶原蛋白和弹性蛋白是维持皮肤弹性和体积的主要成分。这个类型的填充物由于刺激自身蛋白的增生来达到紧致提升的效果,相对自然。可是这个类型的填充物也容易产生结节并且没有溶解的办法。

Biostimulatory Filler choices we offer: Sculptra®,Radiesse®

可选择的再生型填充剂:童颜针,微晶瓷

Fat Emulsifying Agent

In the US, there is only one approved agent in this category, and that is Kybella®. This injectable contains a chemical, sodium deoxycholate, found in bile salts, and therefore will function to emulsify and destroy fat in the treatment area. It can be used in small quantities to reduce and contour fat. 

溶脂针

在美国合法的溶脂针只有kybella这一种。这个溶脂针的有效成分是脱氧胆酸钠,是胆囊中的皂化剂的一种。当注射后可带来局部的脂肪细胞皂化和破裂从而代谢掉而产生脂肪组织缩小的效果。